Warfarin, a vitamin K antagonist has been an effective oral anti-coagulant for over 50 years. It was discovered in 1945 as a result of research at the University of Wisconsin looking into a pesticide for mice and rats. (Patients may need additional management involving certain dental procedures such as extractions)
Source: Feferman I, Healthline: End of an Era (Warfarin), Ontario Dentist, Dec 2011, Vol 88, No 10, pg 16-17.
Hans Skariah, B.Sc., DMD
Promenade Court Dental Health Group in Mississauga
2233 Hurontario St., Mississauga, ON, Canada
(1/2 km north of the QEW in the Dome Building)